About 7% of all men suffer from infertility; pathogenesis male infertility is usually directly related to factors that act at a pre-testicular, post-testicular and testicular level. Testicular failure is the cause for male infertility in approximately 75% percent of men, whereas genetic factors only affect fertility in 15% of men. Even though some progress has been made in this field, especially in the genetics field, causes for pathogenesis male infertility are still unknown in almost 50% of men. These cases are simply diagnosed as “idiopathic infertility”, which means infertility with no known causes. In what concerns genetic disorders or inheritance of fertility issues, these can be caused by congenital absence of vas deferens – meaning the absence of the duct through which semen is carried to the ejaculatory duct –, primitive testicular failure or congenital hypogonadotrophic hypogonadism – which means a failure of the ovaries and, in this case, of the testicles, as a result of hormonal imbalance.
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There is no cure or treatment for most of these issues, but an available option is assisted reproduction, which can have great results even in more severe cases. This is done through sperm extraction, just like women who go through egg retrieval when trying to conceive through in vitro fertilization.
Pathogenesis male infertility can be easy to diagnose, but one must visit a specialist in order to get an accurate diagnosis and appropriate treatment. Men who suffer from infertility should definitely ask for professional help because in some cases this affliction can be reversed or ameliorated. Moreover, pathogenesis male infertility can be connected to other life or health-threatening conditions and immediate treatment is required in those cases. A clear and complete diagnosis of the causes for male infertility is very important because, especially when infertility is related to genetic causes, it can lead to severe issues in any possible offspring. With the help of specialists and treatments, men can avoid any mishaps and make sure their children will be born risk-free.
However, even though pathogenesis male infertility can be helped, there is little progress in pinpointing exact causes and finding how to reverse them. The WHO classification states that a sperm count is normal and the male is well fertile and normal even if up to 70% of his spermatozoa suffer from abnormal morphology, even though such a great number of abnormal spermatozoa are usually related with fertility issues, in both men and animals. This is why a correct diagnosis of fertility problems is so important.